Abstract: Houseflies are the most efficient insects which can adjust themselves according to the surrounding atmosphere.
Seasonality plays a major role in the distribution of houseflies. Occurrence and abundance is also monitored by the weather
conditions, along with the breeding season. Lipids play an important role in protecting these insects in adapting themselves
with change in environment. Summer season is considered as adverse season for thermoregulation of body. Lipid profile is a
major indicative criterion during the change of season and adaptability of these insects. In the present investigation the
experimental design is made in such a manner that lipid profile can be understood in the housefly maggots with the help of
advanced molecular technique MALDI-TOF-MS. The results are discussed in the light available literature and impact of
change of the season on housefly maggots.
Keywords: Houseflies, maggots, lipidomics, MALDI-TOF-MS