Abstract: Coronavirus is single RNA virus . Innovative coronavirus (nCoV) spill out out event, with its epicenter in Wuhan,
People's Republic of China, has appear as a public healthiness disaster of international concern. In this article are mainly
discuss in structure of corona virus then classification life cycle, pathogenesis ,sign and symptom, transmission, death rate .In
this article are mainly focus life cycle and transmission . Coronavirus disease 2019 (COVID-19) is an communicable disease
caused by rigorous acute respiratory disorder coronavirus 2 (SARS-CoV-2). The foremost coronavirus of human origin,
B814, was described in 1965 and since that time only 31 additional strains have been improved. Ten of these were originally
improved in human sprouting tracheal organ cultures only, and the remains in monolayer cell cultures
Keywords: Structure, life-cycle , Classification, Pathogenesis, Transmission.