Abstract: Houseflies are the most common insects. They are considered as a pest because they spread various diseases. These
houseflies are diurnal in habitat and can fly very efficiently and escape from predators easily. They are abundant and very
active especially during the rainy season, due to environmental conditions which are conducive for the houseflies’ survival
and existence. However, during winter season majority of the flies protect themselves from the cold and occupies warmer
places. The most commonest housefly is the Musca domestica which is being extensively studied by various workers especially
entomologist for their role in the environment. An attempt has been made to understand the lipid profile with the help of
lipidomics study of housefly maggots with the help of MALDI-TOF-MS during winter season. The main aim of the study is to
know the protective role of lipids during adverse environmental conditions.
Keywords: Housefly, Musca domestica, lipid profile, MALDI-TOF-MS